Saarland University


Physical Address
Campus Homburg
Building no. 9
66421 Homburg/Germany

Contact Person
Prof. Norbert Graf
At the Faculty of Medicine (University Hospital), located in Homburg/Saarland more than 1800 people are studying medicine. There are 36 hospitals or institutions treating more than 54.000 inpatients and nearly 190.000 outpatients each year. The clinical participant from Saarland University is the department of Paediatric Oncology and Haematology that is responsible for the care of patients in the Saarland and the surrounding area. The research focus of the Department of Paediatric Oncology and Haematology is nephroblastoma and brain tumours (clinical trials and basic research in cooperation with different institutes) and brain tumour.




Key Publications

– Manakis Georgios C, Emmanouilidou Dimitra, Sakkalis Vangelis, Graf N, Marias Kostas,
A fully automated image analysis framework for quantitative assessment of temporal tumor changes,
Proceedings of the 3rd International Conference on E-Health and Bioengineering – EHB 2011, 24-26 November 2011, Iasi, Romania

– Keller A. Petra Leidinger , Andrea Bauer , Abdou Elsharawy , Jan Haas , Christina Backes , Anke Wendschlag , Nathalia Giese , Christine Tjaden , Katja Ott , Jens Werner , Thilo Hackert , Klemens Ruprecht , Hanno Huwer , Junko Huebers , Gunnar Jacobs , Philip Rosenstiel , Henrik Dommisch , Arne Schaefer , Joachim
Mueller-Quernheim , Bernd Wullich , Bastian Keck , Graf N, Jörg Reichrath , Vogel B, Nebel A, Sven Jager , Peer Staehler , Ioannis Amarantos , Valesca Boisguerin , Staehler C, Markus Beier , Matthias Scheffler , Markus W Büchler , Joerg Wischhusen , Sebastian Häusler , Johannes Dietl , Sylvia Hofmann , Hans-Peter Lenhof , Stefan Schreiber , Hugo Katus , Wolfgang Rottbauer , Meder Benjamin , Jörg Hoheisel , Andre Franke , Eckart Meese.
Toward the blood-born miRNome of human diseases,
Nature methods, 8:841-843, 2011 (IF: 20.7, 2009)

– Rossi S, Christ-Neumann ML, Ruping St, Buffa FM, Wegener D, McVie G, Coveney PV, Graf N, Delorenzi M on Behalf of the p-Medicine Consortium (,
p-Medicine: From data sharing and integration via VPH models to personalized medicine,
Ecancer 5:218, 2011;

– Luis Martin, Anguita A, Graf N, Manolis Tsiknaki, Mathias Brochhausen, Stefan Rüping, Anca Bucur, Stelios Sfakianakis, Thierry Sengstag, Fransesca Buffa , Stenzhorn, Holger,
ACGT: Advancing Clinico-genomic trials on cancer. Four years of experience,
Stud Health Technol Inform 169:734-738, 2011 (IF:

– Graf N,
In silico oncology. – Part II : Clinical requirements regarding in silico oncology,
In: Hrsg.: Deisboeck, Thomas S. ; Stamatakos, Georgios S.: Multiscale cancer modeling. – Boca Raton, Fla. : CRC ; London : Taylor & Francis, 2011. – (Chapman & Hall/CRC mathematical and computational biology series ; 34) , S. 437-446

– Brochhausen M, Spear Andrew, Cocos Cristian, Weiler G, Martín Luis, Anguita Alberto, Stenzhorn H, Daskalaki Evangelia, Schera F, Schwarz U, Sfakianakis S, Kiefer S, Dörr M, Graf N, Tsiknakis M,
The ACGT Master Ontology and its Applications – Towards an Ontology-Driven Cancer Research and Management System,
J Biomed Inform 44:8-25, 2011 (IF2.432, 2009)

– Georgios S Stamatakos, Eleni Ch Georgiadi, Graf N, Eleni A Kolokotroni, Dimitra D Dionysiou,
Exploiting clinical trial data drastically narrows the window of possible solutions to the problem of clinical adaptation of a multiscale cancer model,
PLOS one 6:e17594, 2011 (IF: 4.351, 2009)