Institute of Communication and Computer Systems

Physical Address
Institute of Communication
and Computer Systems (ICCS)
9, Iroon. Polytechniou Street
15773 Zografou/Greece

Contact Person
Research Prof. Georgios Stamatakos

The Institute of Communication and Computer Systems (ICCS) is an academic research body affiliated to the National Technical University of Athens (NTUA). It is the research host of the School of Electrical and Computer Engineering of NTUA. It has participated in and coordinated numerous large scale research and development projects funded by the European Commission in both FP6 and FP7 frameworks.

In Silico Oncology Group (ISOG), Laboratory of Microwaves and Fibre Optics, ICCS-NTUA is a world leader in the field of the emergent discipline of in silico oncology. Several novel, clinically driven and clinically oriented simulation models have been developed, tested and disseminated by the In Silico Oncology Group. ISOG has founded the workshop series “International Advanced Research Workshops on In Silico Oncology”. It has also led several actions/workpackages related to in silico oncology in the following EC funded projects: ACGT (Advancing Clinicogenomic Trials on Cancer), ContraCancrum, TUMOR( transatlantic), p-medicine as well as in other international and intercontinental research initiatives. ICCS-NTUA (G. Stamatakos) in collaboration with Massachusetts General Hospital/ Harvard Medical School (T. Deisboeck) co-organized scientifically the First Transatlantic (EU-US) Workshop on Multiscale Cancer Modeling (ICT 2008, Brussels 2008). The latter was co-funded by EC and the National Cancer Institute (NCI), US. A multi-author, transatlantic CRC textbook partly based on the workshop lectures was published in 2010/2011.



Key Publications

– Stamatakos, G. S., Kolokotroni, E. A., Dionysiou, D. D., Georgiadi, E. C. & Desmedt, C.,
An advanced discrete state–discrete event multi-scale simulation model of the response of a solid tumor to chemotherapy: Mimicking a clinical study,
Journal of theoretical biology 266, 124–139 (2010).

– G.S.Stamatakos, E.Ch.Georgiadi, N.Graf, E.A.Kolokotroni, and D.D.Dionysiou,
Exploiting Clinical Trial Data Drastically Narrows the Window of Possible Solutions to the Problem of Clinical Adaptation of a Multiscale Cancer Model,
PLOS ONE 6(3), e17594, 2011

– G.Stamatakos,
In Silico Oncology Part I: Clinically Oriented Cancer Multilevel Modeling Based on Discrete Event Simulation,
In T.Deisboeck and G. Stamatakos Eds 407-436 2011-01-01 CRC Press, Print ISBN: 978-1-4398-1440-6 eBook ISBN: 978-1-4398-1442-0 DOI: 10.1201/b10407-19 Boca Raton, Florida, USA, 2011

– D.D. Dionysiou, G.S. Stamatakos, D. Gintides, N. Uzunoglu, K. Kyriaki,
Critical Parameters Determining Standard Radiotherapy Treatment Outcome for Glioblastoma Multiforme: A Computer Simulation.
The Open Biomedical Engineering Journal 2, 43-51, 2008

– D.D.Dionysiou and G.S.Stamatakos,
Applying a 4D multiscale in vivo tumor growth model to the exploration of radiotherapy scheduling: the effects of weekend treatment gaps and p53 gene status on the response of fast growing solid tumors,
Cancer Informatics, 2, 113-121, 2006

– D.D.Dionysiou, G.S. Stamatakos, N.K.Uzunoglu, K.S.Nikita, A. Marioli,
A Four Dimensional In Vivo Model of Tumour Response to Radiotherapy: Parametric Validation Considering Radiosensitivity, Genetic Profile and Fractionation ,
J. Theor. Biol. , 230 , 1-20 , 2004

– G.S. Stamatakos, D.D. Dionysiou, E.I. Zacharaki, N.A. Mouravliansky, K.S.Nikita, N.K. &amp Uzunoglu,
In silico radiation oncology: combining novel simulation algorithms with current visualization techniques,
IEEE Proceedings: Special Issue on Bioinformatics: Advances and Chalenges , 90(11) , 1764-1777 , 2002